Bence Jones - screening
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BJ
Synonyms
- Bence Jones proteinuria
- Bence Jones protein
- Thermal soluble protein
- Detection of free light chains
- Urine proteins immunoelectrophoresis
Clinic significance
Bence Jones proteins (BJP) are monoclonal kappa or lambda immunoglobulin light chains which are over-expressed by the clone involved in malignant plasma cell dyscrasia, e.g. a myeloma. They are of relatively low molecular weight, pass into the urine and are nephrotoxic. BJP may be present and detectable at a range of different total urine protein levels and, in some cases, this overall level can even be normal.
Prenalytics
- 2 tube(s)
- 24hr Urine collection or Early morning urine
- Refrigerated
Further information
- IMPORTANT: collection and transportation at +4°C
Urine WITHOUT preservative and WITHOUT addition of acid
Specify diuresis - Join the information relating to electrophoresis and serum immunofixation
Specific equipment available
Tube for urine sample (4mL)-T28
Methodology
Immunofixation
Turnaround time
3 days
Pathologist(s) in charge
Biomnis Paris
Specialty
Biochemistry
Contact(s)
Dr Nihad MEKNACHE
Dr Laurence GUIS
Dr Laurence GUIS
Phone(s)
+331 49 59 63 40
+331 49 59 15 01
+331 49 59 15 01