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Bence Jones - screening

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Eurofins Biomnis code

BJ

Synonyms

  • Bence Jones proteinuria
  • Bence Jones protein
  • Thermal soluble protein
  • Detection of free light chains
  • Urine proteins immunoelectrophoresis

Clinic significance

Bence Jones proteins (BJP) are monoclonal kappa or lambda immunoglobulin light chains which are over-expressed by the clone involved in malignant plasma cell dyscrasia, e.g. a myeloma. They are of relatively low molecular weight, pass into the urine and are nephrotoxic. BJP may be present and detectable at a range of different total urine protein levels and, in some cases, this overall level can even be normal.

Prenalytics

  • 2 tube(s)
  • 24hr Urine collection or Early morning urine
  • Refrigerated

Further information

  • IMPORTANT: collection and transportation at +4°C
    Urine WITHOUT preservative and WITHOUT addition of acid
    Specify diuresis
  • Join the information relating to electrophoresis and serum immunofixation

Specific equipment available

Tube for urine sample (4mL)-T28


Methodology

Immunofixation

Turnaround time

3 days


Pathologist(s) in charge
Biomnis Paris
Specialty
Biochemistry
Contact(s)
Dr Nihad MEKNACHE
Dr Laurence GUIS
Phone(s)
+331 49 59 63 40
+331 49 59 15 01