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Cholinesterase - Enzymatic activity - serum

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Eurofins Biomnis code

CHOLI

Synonyms

  • Butyrylcholinesterase
  • Pseudocholinesterase

Clinic significance

Cholinesterase is an enzyme that catalyses the hydrolysis of acetylcholine into acetate and choline. Dosing is recommended in the event of any suspicion of organophosphate intoxication (OP), with anticholinesterase activity: OP inhibits cholinesterase at cholinergic synapses and prevent the breakdown of acetylcholine.
Dosing of cholinesterase also allows the evaluation of hypersensitivity of patients pre-operatively to muscle relaxation anaesthesia (succinylcholine) corresponding to a congenital deficit with reduced butyrylcholinesterase levels.

Prenalytics

  • 1 mL
  • Non haemolysed serum
  • Refrigerated

Further information

  • 1 individual aliquot for this analysis.
  • Plasma with sodium fluoride refused (inhibits cholinesterase)

Methodology

Enzymatic activity by colorimetric kinetics

Turnaround time

2 days


Pathologist(s) in charge
Biomnis Paris
Specialty
Biochemistry
Contact(s)
Dr Isabelle PETIT
Dr Dominique ENGERAND
Phone(s)
+331 49 59 16 72
+331 49 59 62 70