Eurofins Biomnis code

EBVQ

Synonyms

• EBV

Clinic significance

Epstein Barr virus (EBV) belongs to the Herpesviridae family. Primary infection is very frequent and often asymptomatic in children. EBV can cause Infectious Mononucleosis (IM) in adolescents and young adults. Diagnosis is based on serology and, in very rare cases where serology is uninterpretable, on detection of the viral genome in the blood. IMD can sometimes cause hepatic, neurological, haematological, cardiac and pulmonary complications. In immunocompetent patients, asymptomatic reactivations are frequent and are associated with salivary excretion of the virus.

EBV also causes lymphoproliferative syndromes in immunocompetent patients (lymphoma, nasopharyngeal carcinoma) and in immunocompromised patients (post-transplant lymphoproliferative syndrome, lymphoma). These manifestations are the result of the presence of the virus in latent form in B lymphocytes. Certain viral proteins cause them to proliferate. Measuring the EBV viral load in the blood helps in the diagnosis and monitoring of these diseases.

Prenalytics

• 1 mL
• Whole blood or plasma (EDTA), serum: Quantitative result
• Refrigerated

Further information

• The use of the S14UK transport bag is Mandatory.
• .

Documents to download

• information note (N23-INTGB)

Methodology

Real-time PCR

Turnaround time

3 days