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Factor IX - Antihaemophilic B - plasma

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Eurofins Biomnis code

FAC9

Synonyms

  • Antihaemophilic factor B
  • Antihaemophilic B - factor

Clinic significance

Congenital Factor IX deficiency is responsible for hemophilia B. Such deficiency has been attributed to nearly 800 different genetic polymorphisms. Hemophilia is an X-linked disease. The severity of the disease is directly proportional to the levels of Factor IX in the blood with severe hemophilia at below 0,01 kIU/L (1% of normal) and minor disease at levels of over 15%. One third of female carriers have levels of this glycoprotein of between 15 and 50% of the normal. Since Factor IX synthesis is hepatic and depends on vitamin K stimulation, both liver disease and vitamin K-antagonist drugs can induce deficiency.

Prenalytics

  • 2 mL
  • Citrated Plasma
  • FROZEN

Further information

  • Single tube possible for VIII, IX, XI,XII
    The factors VIII, IX, XI,XII (aPTT factors) assay requires at least 2 mL of citrated plasma frozen.
  • Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.)
  • It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.
  • Enclose the specific clinical information form (R5-INTGB : Haemostasis)

Methodology

Chronometric method

Turnaround time

2 days


Pathologist(s) in charge
Biomnis Paris
Specialty
Haematology
Contact(s)
Dr Léna LE FLEM
Dr Dominique ENGERAND
Dr Laurence GUIS
Phone(s)
+331 49 59 17 44
+331 49 59 62 70
+331 49 59 15 01