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Retinol-Binding Protein - RBP

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Eurofins Biomnis code

RBP

Synonyms

  • RBP

Clinic significance

Retinol Binding Protein (RBP) is a non-glycosylated alpha-globulin secreted by the liver which transports vitamin A in the form of retinol complexed with prealbumin. The retinol circulates to the tissues where it is required ((the skin, mucous membranes, retina, etc.). Free RBP passes into the glomerular filtrate but is reabsorbed and then metabolized.
RBP levels rise during fatty change and chronic renal insufficiency proximal tubular dysfunction.
Reduced levels are associated with vitamin A deficiency, tubular nephritis, colorectal cancer, liver disease, severe inflammation and acute malnutrition.
The test is more sensitive than N acetyl-betaglucosaminidase and correlates well with beta -2-microglobulin

Prenalytics

  • 1 mL
  • serum
  • Refrigerated

Further information


    Methodology

    Nephelometry

    Turnaround time

    2 days


    Pathologist(s) in charge
    Biomnis Paris
    Specialty
    Biochemistry
    Contact(s)
    Dr Jean Marc VANDERNOTTE
    Phone(s)
    +331 49 59 63 01