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Clonidine test

List of dynamic tests
Purpose

To investigate somatotropic function by stimulating growth hormone production.

Subject preparation

Subject fasting for 12 hours and at rest for 30 min.

Product

Clonidine (Catapressan®, 0.150 mg tablets) Boehringer Ingelheim France.

Dose

One 0.150 mg Catapressan® tablet.

Protocol
  • Samples (dry tubes) at time intervals: -15 min (T-15) and 0 (T0).
  • Oral administration of one Catapressan® tablet.
  • Samples (dry tubes) at time intervals T+30, T+45, T+60, T+90 and T+180 min.
Samples

After centrifugation, freeze serum at –20°C.

Side effects
  • Close medical supervision is required due to the risk of HYPOTENSION
  • Check pulse and blood pressure every 30 min.
  • If blood pressure drops or the patient feels faint, administer one 100 mg vial of hydrocortisone sodium succinate.
Assay

Growth Hormone (GH).

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