List of dynamic tests
Purpose
To investigate somatotropic function by stimulating growth hormone production.
Subject preparation
- Fasting for 12 hours and at rest for 30 minutes.
Product
Ornithine oxoglutarate (Ornicetyl ®) (2-5 g vials).
Dose
- Adults: 20 g.
- Children: 20 g/m2 body surface area, without exceeding 20 g (10 g if under 7).
After the dose has been calculated, dissolve the product in 200 ml of normal saline (100 ml for 10 g).
Protocol
- Samples (dry tubes) at time intervals: T-15 min and T0.
- IV perfusion of the ornithine over 30 minutes.
- Draw blood (dry tubes) T+30, T+45, T+60, T+90 and T+120 min after the beginning of perfusion.
Samples
Centrifuge the samples and freeze the serum at -20°C.
Assay
Growth Hormone (GH).
Side effects
Risk of nausea and sometimes vomiting.
