List of dynamic tests
Purpose
To investigate adrenocortical function after stimulation with an ACTH analogue.
Product
Tetracosactide (Synacthen®, 0.25 mg / 1 ml vial).
Dose
- Adults: 0.25 mg (1 vial).
- Children: 0.25 mg/m2 body surface area (do not exceed 0.25 mg).
Protocol
- Fasting for 12 hours and at rest for 30 min.
- Sample (dry or EDTA tube) at time interval 0 (8 a.m.) (T0).
- IM injection of the correct dose of Synacthen®.
- Samples (dry or EDTA tubes) according to the doctor’s instructions or T+30 and T+60 min after the Synacthen® injection.
Samples
After centrifugation of the samples, store the serum or plasma at +4°C.
Assays
Cortisol and/or: 17-hydroxyprogesterone, 21-deoxycortisol, 11-deoxycortisol, 17-hydroxypregnenolone, dehydroepiandrosterone, androstenedione, 11-deoxycorticosterone, aldosterone.
Contraindications
- Allergy.