17-Hydroxyprogesterone - serum

Biomnis code

17OHP

Synonyms

• 17-OH-P
• Progesterone, 17-OH-
• 17-OH progesterone
• 17-Hydroxyprogesterone
• 17-alpha-Hydroxyprogesterone

Clinic significance

Intermediate steroid in glucocorticoid and androgen biosynthesis, from progesterone and/or 17-OH-pregnenolone. It is metabolised to delta-4-androstenedione (androgen pathway) or 11-deoxycortisol (glucocorticoid pathway). The urinary catabolite is pregnanetriol. The interest of its assay lies in the analysis of hyperandrogens associated with an andrenal 21-hydroxylase enzyme deficiency. Circadian rhythm.

Preanalytical

• 1 mL
• Serum
• Refrigerated

Further information

• Specify the age, sex and phase of the cycle. For women, the sample must be taken at the start of the follicular phase

Methodology

Radioimmunoassay

Turn around Time

3 days