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HomeServicesTest guideTrisomy 21 - maternal serum markers - 2 parameters - serum
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Trisomy 21 - maternal serum markers - 2 parameters - serum

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Eurofins Biomnis code

21T

Synonyms

  • Serum markers for Trisomy 21
  • HT21
  • Down syndrome
  • Serum screening for Trisomy 21 risk
  • T21 - serum markers
  • T21 MSM

Clinic significance

A set of tests for pregnant women based on two or three markers (free beta hCG, AFP and, on request unconjugated estriol) carried out between 15 and 20 completed weeks of gestation. Software, specially designed for the reagents used, calculates the risk of Down syndrome and non-closure of the neural tube from the test results together with relevant data provided by the subject's physician (the mother's date of birth and weight, and the term of the pregnancy - preferably estimated on the basis of ultrasound data). When the risk of Down's syndrome is greater than 1/250, fetal chromosome analysis is recommended.

Prenalytics

  • 3 mL
  • Serum (do not use plasma)
  • Refrigerated

Further information

  • Non hemolysed, non-icteric, non lipemic sample. Sample must be centrifuged as quickly as possible and international samples must be frozen within 4 hours of sampling.
    Please conserve an additional sample in your serolibrary until you have received the result.
    In accordance with French regulation, ALWAYS attach the prescription, a copy of the ultrasound report and a copy of the patient consent form, signed by both the patient and the physician.

Documents to download


Methodology

Fluoro-Immunoassay (time resolved)

Turnaround time

3 days


Pathologist(s) in charge
Biomnis Lyon
Specialty
Down Syndrome screening and foetal biochemistry
Contact(s)
Dr Corinne SAULT
Dr Alain LIQUIER
Dr Gérard PERAZZA
Dr Marc NOUCHY
Phone(s)
+334 72 80 73 75
+334 72 80 23 61
+334 72 80 23 18
+334 72 80 23 30

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