Trisomy 21 - maternal serum markers - 2 parameters - serum
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21T
Synonyms
- T21 MSM
- HT21
- Down syndrome
- Serum screening for Trisomy 21 risk
- T21 - serum markers
- Serum markers for Trisomy 21
Clinic significance
A set of tests for pregnant women based on two or three markers (free beta hCG, AFP and, on request unconjugated estriol) carried out between 15 and 20 completed weeks of gestation. Software, specially designed for the reagents used, calculates the risk of Down syndrome and non-closure of the neural tube from the test results together with relevant data provided by the subject's physician (the mother's date of birth and weight, and the term of the pregnancy - preferably estimated on the basis of ultrasound data). When the risk of Down's syndrome is superior or equal at 1/50, the foetal karyotype is covered by French social security .
When the risk is between 1/51 and 1/1000, screening by circulating free fetal DNA (NIPT) is covered by the CPAM.
(applicalble for French lab only).
Prenalytics
- 3 mL
- Serum (do not use plasma)
- Refrigerated
Further information
- Non hemolysed, non-icteric, non lipemic sample. Sample must be centrifuged as quickly as possible and international samples must be frozen within 4 hours of sampling.
Please conserve an additional sample in your serolibrary until you have received the result.
In accordance with French regulation, ALWAYS attach the prescription, a copy of the ultrasound report and a copy of the patient consent form, signed by both the patient and the physician.
Documents to download
Methodology
Fluoro-Immunoassay (time resolved)
Turnaround time
3 days
Pathologist(s) in charge
Specialty
Contact(s)
Dr Alain LIQUIER
Dr Marc NOUCHY
E-mail(s)
Phone(s)
+334 72 80 23 61
+334 72 80 23 30