Abacavir - plasma Referred Test
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ABACA
Synonyms
- Kivexa®
- Triumeq®
- Trizivir®
- Ziagen®
Specialty
Analytical Chemistry
Clinical significance
HIV antiretroviral, nucleoside analogue, inhibits HIV 1 reverse transcriptase. Oral bioavailability of the order of 80 %, half-life of approximately 1hr30. Its uptake is not modified by the intake of food. Shows good meningeal diffusion. Possible hypersensitivity reactions during the first 6 weeks of treatment. All respiratory, skin or digestive symptoms require an urgent examination. Never represcribe after discontinuation due to intolerance. Risk of lactic acidosis in patients suffering from hepatopathy or obese patients.
Preanalytics
- 3 mL :
- EDTA Plasma centrifuged immediately
- FROZEN
- Freezing within 4 hours
- A tube specifically for this analysis : No
Further information
Enclose the specific clinical information form (R6-INTGB : Anti-retroviral medicines)
Recommended residual rate, once steady state is reached
Documents to download
Methodology
HPLC - High Performance Liquid Chromatography
Turnaround time
3 weeks
Refered Test
Caption
The pre-analytical conditions and prices are defined on the basis of the requirements of the performing laboratory.