ACTH - Corticotrophin
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ACTH
Synonyms
- Adrenocorticotropic hormone
- Corticostimulin
- Corticotrophin
- Corticotropin
- Endocrinologie
Specialty
Biochemistry
Clinical significance
A polypeptide hormone synthesized by the corticotroph cells of the anterior pituitary gland. This test is useful in the investigation of adrenocortical insufficiency, congenital hyperplasia of the adrenal gland and hyperadrenocorticism.
Preanalytics
- 1 mL :
- Plasma EDTA + Aprotinine - not hemolysed
- FROZEN
- Freezing within 4 hours
- A tube specifically for this analysis : Yes
Further information
If need be to specify a sample taken in the morning or in the evening, please select the specific analysis codes:
Sampling done between 7 a.m. and 10 a.m .: ACTHM
Sampling done in the evening: ACTHS
If sampling on EDTA tube: on cooled tube, refrigerated centrifugation, immediate decantation and freezing
Not to to be performed on haemolysed sample
1 individual aliquot for this analysis.
CIRCADIAN RHYTHM: This biological molecule has a circadian rhythm (maximum concentration in morning), with a sufficiently significant amplitude to have an important influence on the clinical interpretation
ATTENTION: interference possible in patients treated with biotin (vitamin B7, B8 or H) or taking any food supplement containing biotin. Essential to STOP treatment 8 days before taking the sample.
Specific equipment available
- T2 : EDTA + aprotinine tube
Methodology
Electrochemiluminescence
Turnaround time
1 day
Biomnis Ivry