Adenovirus - direct diagnosis - PCR
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ADNVB
Specialty
Infectious
Clinical significance
In immunocompetent patients, adenoviruses can cause upper respiratory tract infections (pharyngitis), lower respiratory tract infections (sometimes severe), gastroenteritis (serotype 40-41 responsible for 5% of viral gastroenteritis in children), conjunctivitis and keratoconjunctivitis (possible epidemics). After infection, the virus may be excreted for several months in the faeces and urine. In immunocompromised patients (especially after bone marrow transplants), disseminated infections may occur, with non-specific symptoms (fever, pneumonia, hepatitis). Detection of viral DNA by PCR has become the reference technique for severe infections in immunocompetent patients and for the prevention and diagnosis of disseminated infections in immunocompromised patients.
Preanalytics
- :
- Respiratory, eye, stool, urine, serum, plasma or whole blood samples EDTA,
- Reftrigerated
- A tube specifically for this analysis : No
Further information
[To be translated]
The use of the S14UK transport bag is Mandatory.
Swab samples require the use of a transport medium (viral) supplied in kit K1.
Samples (other than swabs) must be sent as they are, in sterile bottles, without transport medium.
Specific equipment available
- S14: Special mycobacteria transport bags are to be used
Documents to download
Methodology
Real-time PCR
Turnaround time
6 days
Biomnis Lyon