Eurofins Biomnis code

ALDOU

Synonyms

• Endocrinology
• Mineralocorticoid
• Tetra Hydro aldosteron

Specialty

Biochemistry

Clinical significance

The major mineralocorticoid hormone synthesized in the zona glomerulosa of the adrenal cortex. The rate of its secretion depends on three factors: the blood potassium concentration, corticotropin and the renin-angiotensin system. Aldosterone levels are high in primary aldosteronism (which is characterized by high blood pressure, polydipsia, polyuria with very dilute urine, asthenia and sometimes episodes of tetanus). Hypoaldosteronism is rare and may be secondary to some primary insufficiency (e.g. Addison's disease). Aldosterone levels are affected by certain drugs including spironolactone, diuretics, angiotensin-converting enzyme inhibitors, laxatives, beta-adrenoreceptor-blockers and stimulants, and oral contraceptives. Anti-hypertensive drugs and calcium inhibitors have no effect on aldosterone levels.

Preanalytics

• 1 tube(s) :
• urine
•   FROZEN
• Freezing within 4 hours

• A tube specifically for this analysis : No

Further information

Specify diuresis
DIET INFORMATION: our reference ranges are only valid for a normal salt intake (80-250mEq/24hrs natriuresis )

Specific equipment available

• Tube for urine sample (4mL)-T28

Methodology

Radioimmunoassay

Turnaround time

5 days