Eurofins Biomnis code

ALFA1

Synonyms

• Alpha-1 Antitrypsin
• A1 Antitrypsin
• Pi - Protease inhibitor
• Protease inhibitor

Specialty

Biochemistry

Clinical significance

Alpha-1-antitrypsin (A1AT) is a glycoprotein synthesized in the liver which is found in most biological fluids and in the feces. It inactivates a wide range of proteolytic enzymes including elastase, chymotrypsin, trypsin and cathepsin. It is also involved in inhibiting Factor XIIa and kallikrein Biochemical polymorphisms of A1AT constitute the Pi (Protease inhibitor) system.A1AT levels rise during pregnancy and can fall as a result of heavy consumption at a focus of inflammation. Congenital deficiencies in this enzyme are associated with variably decreased levels in the serum.

Preanalytics

• 1 mL :
• Serum
•   Reftrigerated

• A tube specifically for this analysis : No

Further information

Please specify the patient gender, age and the possible treatment (ALFALASTIN)

Methodology

Nephelometry

Turnaround time

2 days