Tissue plasminogen activator - tPA - antigen - plasma

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Eurofins Biomnis code

APLA

Synonyms
  • t-PA
Specialty

Haematology


Clinical significance

Tissue plasminogen activator (t-PA) is one of the physiological activators of plasminogen. Important in fibrinolysis. t-PA levels are increased in a wide variety of different pathological conditions including respiratory distress, myocardial infarction, shock, septicemia and serious liver damage. Defective t-PA release from the endothelium compromises the fibrinolytic process and is therefore a thrombotic risk factor.WARNING: not to be confused with the other TPA test - "Tissue Polypeptide Antigen" - which is a tumor marker and for which the specimen must be frozen. All orders must be filled out with the name in full rather than the acronym.

Preanalytics
  • A tube specifically for this analysis : Yes
Further information

1 individual aliquot for this analysis.
Please label the request in words and do not use abbreviations
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.


Methodology

Enzyme-immunoassay

Turnaround time

1 month


Testing Laboratory

Biomnis Ivry