Eurofins Biomnis code

B27BM

Synonyms

• HLA-B27 antigen
• HLA-B27 genotyping
• HLA-B27 leukocyte and platelet antigens
• HLA-B27 typing

Specialty

Genetics

Clinical significance

The HLA B27 haplotype is strongly associated with ankylosing spondylitis; most patients with this disease are HLA B27-positive (although only a small fraction of all people with this haplotype actually develop the disease). This haplotype is also associated with secondary arthritis, Reiter's syndrome and acute anterior uveitis, although with these conditions the correlation is not so close.

Preanalytics

• 5 mL :
• Whole blood EDTA, avoid tubes containing beads.
•   Ambient temperature

• A tube specifically for this analysis : No

Further information

According to regulation, each request must ALWAYS be accompanied by a consent form signed by the patient and the prescribing pathologist
Enclose the specific B12-INTGB request form: Molecular Genetics
.

Documents to download

• Specific Request Form (B12-INTGB)
• [To be translated]

Methodology

Real-time PCR

Turnaround time

4 days