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HLA-B27 - genotyping

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Eurofins Biomnis code

B27BM

Synonyms

  • HLA-B27 leukocyte and platelet antigens
  • HLA-B27 genotyping
  • HLA-B27 typing
  • HLA-B27 antigen

Clinic significance

The HLA B27 haplotype is strongly associated with ankylosing spondylitis; most patients with this disease are HLA B27-positive (although only a small fraction of all people with this haplotype actually develop the disease). This haplotype is also associated with secondary arthritis, Reiter's syndrome and acute anterior uveitis, although with these conditions the correlation is not so close.

Prenalytics

  • 5 mL
  • Whole blood EDTA, avoid tubes containing beads.
  • Ambient temperature

Further information

  • .
  • According to regulation, each request must ALWAYS be accompanied by a consent form signed by the patient and the prescribing pathologist
  • Enclose the specific B12-INTGB request form: Molecular Genetics

Methodology

Real-time PCR

Turnaround time

4 days


Pathologist(s) in charge
Biomnis Lyon
Specialty
Genetics
Contact(s)
Dr Marc NOUCHY
Dr Laure RAYMOND
Dr Nicole COUPRIE
Dr Thibaut BENQUEY
Phone(s)
+334 72 80 23 30
+334 72 80 25 77
+334 72 80 10 04
+334.72.80.25.77