Barbiturates - urine
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BARBU
Specialty
Analytical Chemistry
Clinical significance
Barbiturates are prescribed as anticonvulsants, sedatives and hypnotics.Detection of these compounds in the serum, urine or gastric juice for toxicological purposes is based on a qualitative immunoassay. The antibody used was actually raised against secobarbital but it recognizes all barbiturates (with varying affinity) without interference from corresponding hydroxylated derivatives.In order to interpret the results, the class of barbiturate concerned must be taken into account. Barbiturates with a short half-life induce far fewer side effects than longer-acting members of the class like phenobarbital. Acute overdosage could result in drowsiness followed by deep coma with respiratory depression, hypothermia, hypotension and anuria.
Further information
[To be translated]
Specific equipment available
- Tube for urine sample (4mL)-T28
Methodology
Homogeneous phase enzyme-linked immunosorbent technique
Turnaround time
2 days
Biomnis Ivry