Benzodiazepines - screening without identification - Serum

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Eurofins Biomnis code

BENZS

Synonyms
  • Benzo
  • BZD
Specialty

Analytical Chemistry


Clinical significance

Benzodiazepines are prescribed as sedatives, anxiolytics and antiepileptics. Poisoning may be either accidental or deliberate.Detection of these compounds in the serum, urine or gastric juice for toxicological purposes is based on a qualitative immunoassay. The antibody used was actually raised against demethyl-diazepam but it cross reacts with a wide range of different benzodiazepines and their metabolites. Distinguishing between different benzodiazepines or metabolites and quantitative determination depends on HPLC.

Preanalytics
  • A tube specifically for this analysis : No
Further information

The samples can be frozen and thawed 3 times.
[To be translated]


Methodology

Homogeneous phase enzyme-linked immunosorbent technique

Turnaround time

1 day


Testing Laboratory