Eurofins Biomnis code

BJ

Synonyms

• Bence Jones protein
• Bence Jones proteinuria
• Detection of free light chains
• Thermal soluble protein
• Urine proteins immunoelectrophoresis

Specialty

Biochemistry

Clinical significance

Bence Jones proteins (BJP) are monoclonal kappa or lambda immunoglobulin light chains which are over-expressed by the clone involved in malignant plasma cell dyscrasia, e.g. a myeloma. They are of relatively low molecular weight, pass into the urine and are nephrotoxic. BJP may be present and detectable at a range of different total urine protein levels and, in some cases, this overall level can even be normal.

Preanalytics

• 2 tube(s) :
• Urine 24-hour sample or morning urination
•   Reftrigerated

• A tube specifically for this analysis : No

Further information

IMPORTANT: collection and transportation at +4°C
Urine WITHOUT preservative and WITHOUT addition of acid
Specify diuresis
Join the information relating to electrophoresis and serum immunofixation

Specific equipment available

• Tube for urine sample (4mL)-T28

Methodology

Immunofixation

Turnaround time

2 days