Eurofins Biomnis code

C3NEF

Synonyms

• Nephritic factor

Specialty

Immunology

Clinical significance

C3 Nephritic Factor or C3 NeF is an autoantibody which stabilizes the C3b,Bb complex, a C3 convertase in the alternative complement fixation pathway .C3 NeF is found stabilizing alternative pathway C3 convertase in Type II membranoproliferative glomerulonephritis otherwise known as dense deposit disease. It is also associated with partial lipodystrophy in which it acts on adipsin.

Preanalytics

• 1 mL :
• serum
•   Reftrigerated

• A tube specifically for this analysis : No

Further information

Specify C3 value
Stability 7 days refrigerated

Methodology

Immuno chemistry

Turnaround time

6 weeks

Caption