Eurofins Biomnis code

CALP

Specialty

Analytical Chemistry

Clinical significance

Calprotectin is present in large amount in Granulocytes. Presence in stool reflects bowels inflamation. Quantification may be useful for bowels inflamatory Dieseases diagnosis or follow-up. In adults and children over the age of 4, faecal calprotectin measurement is therefore used :In the context of an IBD diagnostic referral: a negative result means that digestive inflammation can be ruled out and the invasive and costly procedure of medical imaging can be avoided. In the context of IBD follow-up: a negative result indicates a state of remission, with or without healing of the mucosa. A positive result, depending on its intensity, can show whether the inflammation has progressed to a stage requiring an endoscopic procedure and/or a change in treatment. In children from birth to 4 years of age, the faecal calprotectin assay helps paediatricians to diagnose IBD, thanks to 4 positivity thresholds based on 4 age groups.

Preanalytics

•  :
• Stool
•   Refrigerated

• A tube specifically for this analysis : No

Further information

Sample
Enclose the specific clinical information form (R29-INTGB : Functional Coprology)

Specific equipment available

• Use small white coprology jars

Documents to download

• Specific clinical information form (R29-INTGB)

Methodology

chimiluminescence (CLIA) de DIASORIN sur Liaison XL

Turnaround time

2 days