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Anti-potassium channel antibodies / Lgi1 Caspr2 - serum

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Eurofins Biomnis code

CAPO

Synonyms

  • anti-Caspr2 antibodies
  • Anti-VGKC antibodies
  • Potassium channels - anti-antibodies
  • anti-Lgi1 antibodies

Clinic significance

1. Anti-Lgi1 autoantibodies are commonly associated with anti-VGKC in limbic encephalitis not associated with paraneoplastic syndrome.

2. Anti-Caspr2 antibodies are more commonly associated with neuromyotonia, Morvan's syndrome; with limbic encephalitis associated with tumours, thymoma and small-cell lung cancer.

Prenalytics

  • 500 µL
  • serum (do not use 10 mL tube)
  • Refrigerated

Further information

    Methodology

    Immunofluorescence

    Turnaround time

    1 week

    Pathologist(s) in charge
    Biomnis Lyon
    Specialty
    Immunology
    Contact(s)
    Dr Alexia BARBRY
    Dr Anne OVIZE
    Phone(s)
    +334 72 80 23 18
    +334 72 80 73 05