Eurofins Biomnis code

CLOZA

Synonyms

• Desmethylclozapine
• Leponex®
• Norclozapine

Specialty

Analytical Chemistry

Clinical significance

A major neuroleptic of the dibenzodiazepine class with strong anti-psychotic activity. Half-life = 12 hours. Test useful for monitoring treatment, establishing the correct dose and detecting evidence of toxicity (especially heart toxicity).

Preanalytics

• 1 mL :
• lithium heparin plasma (do not use tubes with separator gel)
•   Reftrigerated

• A tube specifically for this analysis : Yes

Further information

Enclose the specific clinical information form (R13-INTGB : Medication quantification)
1 individual aliquot for this analysis.
Always draw blood at the same time before another administration
The following examinations can be performed on the same sample: Aripiprazole; Clozapine; Haloperidol; olanzapine; Quétiapine; Rispéridone.

Documents to download

• Specific clinical information form (R13-INTGB)

Methodology

Liquid chromatography / Tandem mass spectrometry (LC-TMS/MS)

Turnaround time

1 week