Eurofins Biomnis code

COXLA

Synonyms

• Enterovirus
• Entérovirus

Specialty

Infectious

Clinical significance

The Enterovirus genus, in the Picornaviridae family, is composed of small non-enveloped RNA viruses. It currently includes more than a hundred serotypes that are pathogenic for humans, divided into five species (poliovirus and human enterovirus A-D - old classification). These viruses are highly resistant in the external environment and are transmitted mainly via the faecal-oral route, but also via the air, conjunctival or transplacental routes. Non-polio enteroviruses are considered to be one of the main causes of viral infection in children and adults. Non-polio enteroviruses include group A and B coxsackie viruses and echoviruses. Although most enterovirus infections are asymptomatic or even paucisymptomatic, these ubiquitous pathogens are responsible for a variety of infectious syndromes. - upper respiratory tract infections (rhinitis, pharyngitis, otitis) or lower respiratory tract infections (pneumonia, bronchiolitis); - damage to the cardiovascular system (myopericarditis, vasculitis, dilated cardiomyopathy); - damage to the nervous system: seasonal lymphocytic meningitis (spring/summer), more rarely encephalitis, or pseudo-poliomyelitic paralytic syndrome; - conjunctivitis - muscular damage: Bornholm disease with myalgic syndrome; - skin damage with rashes and mucous membranes (herpangina and hand-foot-and-mouth syndrome). Newborns may suffer from severe multisystem symptoms. Hand-foot-and-mouth disease and herpangina are more often associated with group A coxsackie viruses, while echoviruses are often responsible for viral meningitis. Excretion occurs via the digestive tract, regardless of the symptoms observed. Testing for the enterovirus genome by real-time RT-PCR in CSF and other peripheral samples (stools, throat swabs, respiratory samples) enables rapid, reliable diagnosis, particularly of meningeal disease.

Preanalytics

• 8 mL :
• amniotic fluid
•   Refrigerated

• A tube specifically for this analysis : No

Further information

Attach the patient's informed consent (D44 consent_Post-Prenatal)
The use of the S14UK transport bag is Mandatory.
Use the specific form B3-INTGB: Cytogenetic

Documents to download

• Specific clinical information form (R10 -INTGB)
• Information note (N23-INTGB)
• Specific clinical information form (D44-INTGB)
• Bon de demande Spécifique (B3-INTGB)

Methodology

Real-time PCR

Turnaround time

4 days