Cushing syndrome panel - Cushing syndrome screening
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CUSH
Specialty
Biochemistry
Preanalytics
- 1 mL refrigerated serum 1 mL frozen plasma 5 mL Salivette® saliva sample 4 mL Non acidified 24hrs urine collection
- A tube specifically for this analysis : No
Further information
Collect the sample in the morning between 7 and 10 am, or according to the instructions from the prescribing party
Not to to be performed on haemolysed sample
Sampling and transportation conditions:
- sampling on EDTA tube: sample on a cooled tube at 4°C, centrifuge at +4°C immediately and FREEZE the plasma immediately
OR
- sampling on special tube (EDTA + Aprotinin) supplied upon request: centrifuge at +4°C and FREEZE the plasma
Specify diuresis
SPECIAL OR DELICATE SAMPLE: the kit used to collect and transport the saliva sample is called a "Salivette". It is available upon request. Before sampling, the patient must observe a time of at least 30 minutes without consuming food or acidic beverages. It is very important not to contaminate the saliva sample with blood, therefore, it is necessary to avoid brushing teeth before collection. The collection protocol is described in the package insert accompanying the sampling kit.
CIRCADIAN RHYTHM: This biological molecule has a circadian rhythm (maximum concentration in morning), with a sufficiently significant amplitude to have an important influence on the clinical interpretation
ATTENTION: interference possible in patients treated with biotin (vitamin B7, B8 or H) or taking any food supplement containing biotin. Essential to STOP treatment 8 days before taking the sample.
Methodology
Electrochimiluminescence Immunoassay (ECLIA) and radioimmunassay
Turnaround time
2 weeks
Biomnis Ivry