Eurofins Biomnis code

DHA

Synonyms

• Dehydro-epiandrosterone
• DHA
• EndocrinologY

Specialty

Biochemistry

Clinical significance

DHEA is a 17-ketosteroid (17-oxosteroid) produced from 17-hydroxy-pregnenolone. It is metabolized to form delta-4-androstenedione and testosterone. In women, 50% of DHA is synthesized in the adrenal gland, 25% in the ovaries and 25% by the conversion of DHA sulfate. In patients with 3-beta-hydroxy-dehydrogenase deficiency, DHEA levels rise in a short Synacthen (adrenocortical stimulation) test. High levels are observed in the absence of stimulation in precocious puberty and in adrenal hyperplasia due to 11-beta-hydroxylase deficiency and Stein-Leventhal syndrome.

Preanalytics

• 1 mL :
• Serum
•   Reftrigerated

• A tube specifically for this analysis : No

Further information

CIRCADIAN RHYTHM: This biological molecule has a circadian rhythm (maximum concentration in morning), with a sufficiently significant amplitude to have an important influence on the clinical interpretation

Methodology

Radioimmunoassay

Turnaround time

3 days