Eurofins Biomnis code

DHT

Synonyms

• Androstanolone
• Dihydrotestosterone
• Endocrinology
• [To be translated]
• 5-alpha DHT
• 5-alpha-Dihydrotestosterone

Specialty

Biochemistry

Clinical significance

Testosterone is converted into 5-alpha dihydrotestosterone (DHT) by 5-alpha reductase. Nearly all of the DHT found in the peripheral blood is derived from androgens (80% from the conversion of delta-4 androstenedione, 15% from that of testosterone and 5% from the ovaries or adrenal glands). Test useful in the investigation of idiopathic hirsutism or 5-alpha-reductase deficiency (hirsutism.) In 5 alpha reductase deficiency the affected subjects show normal testosterone levels with low levels of DHT. The enzyme deficiency can best be determined by measuring testosterone and DHT after hCG stimulation.

Preanalytics

• 3 mL :
• serum
•   Reftrigerated

• A tube specifically for this analysis : No

Methodology

Chromatography - Extraction - Radioimmunoassay

Turnaround time

6 days