11-Deoxycorticosterone - serum
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DOC
Synonyms
- Corticosterone - 11-Deoxy
- Deoxycorticosterone - 11
- DOC
- Endocrinology
Specialty
Biochemistry
Clinical significance
Produced from progesterone under the effect of 21-hydroxylase, DOC is the immediate precursor of corticosterone and aldosterone. It has a mineralocorticoid action. Its assay is recommended in cases of 11-hydroxylase and 17-alpha-hydroxylase enzyme deficiencies, adrenal tumours and in arterial hypertension analysis.
Further information
CIRCADIAN RHYTHM: This biological molecule has a circadian rhythm (maximum concentration in morning), with a sufficiently significant amplitude to have an important influence on the clinical interpretation
Methodology
LC-MS/MS
Turnaround time
1 week
Testing Laboratory
Biomnis Lyon
Contact(s)
Customer Care