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HomeServicesTest guideTrisomy 21 - maternal serum markers - 3 parameters - serum
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Trisomy 21 - maternal serum markers - 3 parameters - serum

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Eurofins Biomnis code

E21

Synonyms

  • Serum screening for Trisomy 21 risk
  • T21 MSM
  • Down syndrome
  • Serum markers for Trisomy 21
  • T21 - serum markers
  • HT21

Clinic significance

Assays on pregnant women, of two or three markers (free beta hCG, AFP and non-conjugated oestriol on request) between the 15th and 18th week after the last menstrual period (from 14 weeks and 0 days to 17 weeks and 6 days).
The risk of Down's Syndrome and neural tube non-closure is then calculated using a suitable program according to the reagents used, on the basis of the information provided by the prescribing physician (date of birth, date of gestation preferably calculated by ultrasonographic means, weight, smoker/non-smoker) and the marker levels. If the risk of Down's Syndrome is greater than 1/250, the foetal karyotype is covered by French social security (applicalble for French lab only).

Prenalytics

  • 3 mL
  • Serum (do not use plasma)
  • Refrigerated

Further information

  • Non hemolysed, non-icteric, non lipemic sample. Sample must be centrifuged as quickly as possible and international samples must be frozen within 4 hours of sampling.
    Please conserve an additional sample in your serolibrary until you have received the result.
    In accordance with French regulation, ALWAYS attach the prescription, a copy of the ultrasound report and a copy of the patient consent form, signed by both the patient and the physician.

Documents to download


Methodology

Fluoro-Immunoassay (time resolved)

Turnaround time

3 days


Pathologist(s) in charge
Biomnis Lyon
Specialty
Down Syndrome screening and foetal biochemistry
Contact(s)
Dr Corinne SAULT
Dr Alain LIQUIER
Dr Gérard PERAZZA
Dr Marc NOUCHY
Phone(s)
+334 72 80 73 75
+334 72 80 23 61
+334 72 80 23 18
+334 72 80 23 30

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