Isoelectric focussing - CSF + serum

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Eurofins Biomnis code

EPLCR

Synonyms
  • CSF electrophoresis
  • Intrathecal IgG synthesis
  • Isoelectric focussing with IgG index
  • [To be translated]
Specialty

Biochemistry


Clinical significance

The CSF protein isoelectrofocusing technique detects the presence of olioclonal IgG bands in CSF, compared to serum. This olicoglonal aspect specific to CSF IgG indicates intrathecal IgG synthesis and is one of the diagnostic elements of multiple scloerosis.

Preanalytics
  • A tube specifically for this analysis : Yes
Further information

CSF and serum sample taken the same day
1 specific tube for this analysis, especially if joint request of Borreliosis.
No compact or urine container for CSF samples


Methodology

Isoelectric focusing

Turnaround time

4 days


Testing Laboratory