Eurofins Biomnis code

FAC11

Synonyms

• Rosenthal - factor
• Rosenthal factor

Specialty

Haematology

Clinical significance

Congenital factor XI deficiency with dominant autosomal transmission is rare in the general population, with the exception of Ashkenazi Jews. In composite heterozygous or homozygous subjects, the haemorrhagic signs vary: they particularly consist of delayed, moderate, but sustained, bleeding after tooth extraction or adenoid removal. In heterozygous subjects, the haemorrhagic risk should be taken into account (there is no correlation between the factor XI level and the haemorrhagic risk); bleeding is generally caused by wounding actions.

Preanalytics

• 2 mL :
• Citrated Plasma
•   FROZEN
• Freezing within 4 hours

• A tube specifically for this analysis : No

Further information

Enclose the specific clinical information form (R5-INTGB : Haemostasis)
Single tube possible for VIII, IX, XI,XII
The factors VIII, IX, XI,XII (aPTT factors) assay requires at least 2 mL of citrated plasma frozen.
Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.)
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.

Documents to download

• Specific clinical information form (R5-INTGB)

Methodology

Chronometric method

Turnaround time

1 day