Factor XII - Hageman - plasma

Back to the list
Eurofins Biomnis code

FAC12

Synonyms
  • Hageman - factor
  • Hageman factor
Specialty

Haematology


Clinical significance

Factor XII deficiency (usually qualitative) is an autosomal recessive trait. Heterozygotes have Factor XII levels of anywhere between 15 and 80% of the normal level while homozygotes have less than 1%. It has been clearly established that such deficiency is not associated with a tendency to hemorrhage although an increased predisposition to thrombosis remains possible because the main role played by Factor XII in hemostasis is to promote fibrinolysis.Levels of Factor XII in the blood may rise dramatically after intense physical exercise.

Preanalytics
  • A tube specifically for this analysis : No
Further information

Enclose the specific clinical information form (R5-INTGB : Haemostasis)
Single tube possible for VIII, IX, XI,XII
The factors VIII, IX, XI,XII (aPTT factors) assay requires at least 2 mL of citrated plasma frozen.
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.


Methodology

Chronometric method

Turnaround time

1 day


Testing Laboratory

Biomnis Ivry