Factor II - Prothrombin - activity - plasma

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Eurofins Biomnis code

FAC2

Synonyms
  • Prothrombin - activity
Specialty

Haematology


Clinical significance

Congenital prothrombin deficiency is rare although there exist acquired forms due to inadequate vitamin K intake or absorption. In this case, there is also deficiency in Factors VII, IX and X. Deficiency may also be found in liver disease, fibrinolysis and diffuse intravascular coagulation (in which case Factor II deficiency is usually associated with deficiency in Factors V, VII and X).

Preanalytics
  • A tube specifically for this analysis : No
Further information

Enclose the specific clinical information form (R5-INTGB : Haemostasis)
Single tube possible for II, V, VII, X
The factors II, V, VII, X (prothrombin complex factors) assay requires at least 2 mL of citrate plasma frozen
Attach patient¿s clinical details (inflammatory syndrome, pregnancy, family history) and the context of the test prescription request (haemorrhages, thrombosis, preoperative care, replacement therapy...) and any possible therapeutic prescription information.
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.


Methodology

Chronometric method

Turnaround time

1 day


Testing Laboratory

Biomnis Ivry