Factor VII - Proconvertin - plasma

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Eurofins Biomnis code

FAC7

Synonyms
  • Proconvertin
Specialty

Haematology


Clinical significance

A coagulation factor synthesized in the liver and carboxylated in a vitamin K-dependent reaction. Hereditary deficiency is very rare and the heterozygous state usually asymptomatic with about 30% of normal levels. Different forms of deficiency have been reported. Acquired deficiency is more common and can be caused by fibrinolysis, diffuse intravascular coagulation, vitamin K antagonist drugs, inadequate absorption or intake of vitamin K and liver disease. Increased Factor VII levels have been observed during episodes of arterial thrombosis.

Preanalytics
  • A tube specifically for this analysis : No
Further information

Enclose the specific clinical information form (R5-INTGB : Haemostasis)
Single tube possible for II, V, VII, X
The factors II, V, VII, X (prothrombin complex factors) assay requires at least 2 mL of citrate plasma frozen
Attach patient¿s clinical details (inflammatory syndrome, pregnancy, family history) and the context of the test prescription request (haemorrhages, thrombosis, preoperative care, replacement therapy...) and any possible therapeutic prescription information.
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.


Methodology

Chronometric method

Turnaround time

1 day


Testing Laboratory

Biomnis Ivry