Eurofins Biomnis code

FAC9

Synonyms

• Antihaemophilic B - factor
• Antihaemophilic factor B

Specialty

Haematology

Clinical significance

Congenital Factor IX deficiency is responsible for hemophilia B. Such deficiency has been attributed to nearly 800 different genetic polymorphisms. Hemophilia is an X-linked disease. The severity of the disease is directly proportional to the levels of Factor IX in the blood with severe hemophilia at below 0,01 kIU/L (1% of normal) and minor disease at levels of over 15%. One third of female carriers have levels of this glycoprotein of between 15 and 50% of the normal. Since Factor IX synthesis is hepatic and depends on vitamin K stimulation, both liver disease and vitamin K-antagonist drugs can induce deficiency.

Preanalytics

• 2 mL :
• Citrated Plasma
•   FROZEN
• Freezing within 4 hours

• A tube specifically for this analysis : No

Further information

Enclose the specific clinical information form (R5-INTGB : Haemostasis)
Single tube possible for VIII, IX, XI,XII
The factors VIII, IX, XI,XII (aPTT factors) assay requires at least 2 mL of citrated plasma frozen.
Attach the clinical data relating to the patient (major inflammatory syndrome, pregnancy, etc.) and the circumstances (bleeding, thrombosis, preoperative evaluation, etc.)
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.

Documents to download

• Specific clinical information form (R5-INTGB)

Methodology

Chronometric method

Turnaround time

1 day