Eurofins Biomnis code

FIL

Synonyms

• Filaria
• Loa loa filariasis
• Mansonella perstans
• Onchocerciasis

Specialty

Infectious

Clinical significance

Parasitic infections due to nematode filaria which are very common in the Tropics. Diverse diseases are caused by the different species: - Wucheraria bancrofti and Brugia malayi reside in lymphatic vessels and cause elephantiasis; - Loa Loa resides in subcutaneous connective tissue and can induce edematous swellings; - Onchocerca volvulus causes subcutaneous nodules and can progress to blindness. Serology is useful for Onchocerciasis and Loaiasis diagnosis. This test offers a poor detection of lymphatic filariasis and may be subject to crossed-reaction with strongyloides, echinococcus and anisakiasis. It does not allow a species diagnosis. Diagnosis must be made by microfilariae detection in dermic juice (onchocerciasis) or in blood (other filariasis) according to their periodicity. Definitive diagnosis depends on detecting microfilaria in a slit-smear (onchocerciasis) or in the blood (other forms or filariasis).

Preanalytics

• 1 x 1 mL :
• serum (do not use 10 mL tube)
•   Reftrigerated

• A tube specifically for this analysis : No

Methodology

Enzyme-immunoassay

Turnaround time

8 days