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Gastrointestinal Panel - direct diagnosis - PCR

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Eurofins Biomnis code

GIP

Synonyms

  • Plesiomonas shigelloides
  • Shiga-like toxin-producing E. coli (STEC) stx1/stx2
  • Vibrio cholerae
  • Vibrio (V. parahaemolyticus/V. vulnificus/ V. cholerae)
  • Cryptosporidium spp.
  • Enteroaggregative E. coli (EAEC)
  • Cyclospora cayetanensis
  • Shigella/Enteroinvasive E. coli (EIEC)
  • E. coli O157:H7
  • Sapovirus GI/GII/GIV/GV
  • Adenovirus F 40/41
  • Enteropathogenic E. coli (EPEC)
  • Yersinia enterocolitica
  • Salmonella sp
  • Clostridium difficile : toxines A/B
  • Amibes
  • Rotavirus A
  • Norovirus GI/GII
  • Enterotoxigenic E. coli (ETEC) lt/st
  • Astrovirus/Sapovirus
  • Astrovirus
  • Giardia intestinalis
  • Campylobacter (C. jejuni/coli/upsaliensis)
  • Entamoeba histolytica

Clinic significance

The symptomatology of gastrointestinal infections is non-specific, making it difficult to target a specific pathogen. There are a wide number of pathogens responsible for gastrointestinal symptoms, which can be caused by viruses, bacteria (or bacterial toxins) or even parasites. The current medical biology techniques for diagnosing these gastrointestinal infections vary greatly according to the microbiological target (virus, bacteria or parasite) and the specificity of these techniques varies greatly. This is why microbiological documentation of the specific pathology behind gastrointestinal infections is rare. In addition, certain microbiological testing is linked to a medical emergency (e.g. enterohaemorrhagic E. coli toxins or E. coli O157 clone, responsible for haemolytic-uraemic syndrome in children), however these are long and complicated analyses.The use of a gastrointestinal PCR panel resolves these problems, and therefore: - You obtain accurate microbiological documentation, with simultaneous testing for the 32 most frequently responsible pathogens
- You obtain a result in only a few hours from a single stool sample and in one go, using a single technique, which takes approximately one hour.The patient can then be treated quickly and effectively by targeting the isolated pathogen while also reducing the inappropriate use of antibiotics. The gastrointestinal panel tests for the following 32 target pathologies: - Campylobacter (C. jejuni/coli/upsaliensis) - Clostridium difficile: A/B toxins - Plesiomonas shigelloides - Salmonella sp - Vibrio (V. parahaemolyticus/V. vulnificus/ V. cholerae), - Vibrio cholerae - Yersinia enterocolitica Diarrheagenic E. coli/Shigella - Enteroaggregative E. coli (EAEC) - Enteropathogenic E. coli (EPEC) - Enterotoxigenic E. coli (ETEC) lt/st - Shiga-like toxin-producing E. coli (STEC) stx1/stx2 - E. coli O157 - Shigella/Enteroinvasive E. coli (EIEC) Parasites - Cryptosporidium sp - Cyclospora cayetanensis - Entamoeba histolytica - Giardia intestinalis Virus - Adenovirus F 40/41 - Astrovirus - Norovirus GI/GII - Rotavirus A - Sapovirus

Prenalytics

  • Stools
  • Refrigerated

Further information

    Specific equipment available

    S14: Special mycobacteria transport bags are to be used


    Methodology

    Real-time PCR

    Turnaround time

    2 days


    Pathologist(s) in charge
    Biomnis Lyon
    Specialty
    Infectious
    Contact(s)
    Dr Véronique JACOMO
    Dr Xavier NAUDOT
    Phone(s)
    +334 72 80 47 43
    +334 72 80 73 01

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