Eurofins Biomnis code

GLIAA

Synonyms

• Anti DPG antibodies
• Anti-deamidated Gliadin Peptide Antibodies
• Anti-deamidated gliadin peptide antibodies
• Gliadin - anti-IgA antibodies
• [To be translated]

Specialty

Immunology

Clinical significance

A marker for celiac disease - assayed in parallel to the anti-endomysium, anti-transglutaminase and anti-reticulin antibody tests. Useful for deciding whether or not a jejunal biopsy is warranted. The IgG assay is more sensitive but less specific. After commencement of a gluten-free diet, the IgA antibodies disappear within 3 months and the IgG antibodies within 6 months but both reappear if the diet is not maintained.

Preanalytics

• 1 mL :
• serum (do not use 10 mL tube)
•   Reftrigerated

• A tube specifically for this analysis : No

Further information

During the assay of the IgA anti-gliadin antibodies, if there is an alarm causing us to suspect a deficit in total IgA, the assay of total IgA and the assay of anti-transglutaminase IgG antibodies will be carried out in order to make the diagnosis of coeliac disease.

Methodology

Fluorescent enzyme-immunoassay

Turnaround time

3 days