Glucagon - plasma
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GLUC
Synonyms
- Endocrinology
Specialty
Biochemistry
Clinical significance
A blood glucose-raising pancreatic hormone. Glucagon is a small hormonal peptide of 29 amino acids with a molecular weight of about 3550 which plays an important role in glucoregulation. It is secreted by the alpha-cells of the pancreatic islets and opposes the action of insulin by potent activation of glycogenolysis and gluconeogenesis. Hepatic glucose increases within minutes of glucagon stimulation. Increased levels seen in patients with glucagonoma syndrome (due to a very rare tumor).
Preanalytics
- 1 mL :
- EDTA plasma + Aprotinine - non haemolysed
- FROZEN
- Freezing within 4 hours
- A tube specifically for this analysis : No
Further information
Sample on special tube (EDTA + Aprotinin) supplied on request.
Special tube (EDTA + Aprotonin) supplied upon request. Centrifuge at +4°C and FREEZE the plasma immediately.
Specific equipment available
- T2 : EDTA + aprotinine tube
Methodology
Radioimmunoassay
Turnaround time
2 weeks (if dilution/control needed - TAT 4 weeks
Biomnis Ivry