Helicobacter pylori - 13C urea breath test - expired gas
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HKIT
Synonyms
- Breath test
- Hp - 13C-urea breath tests
- 13C-urea breath tests - Helicobacter pylori
Specialty
Infectious
Clinical significance
This test is based on the fact that Helicobacter pylori (Hp) has strong urease activity. After oral administration of ¹³C-urea (a stable isotope of carbon), expiration of ¹³CO2-rich gas is suggestive of the presence of Hp.This non-invasive test is simple to perform (specificity > 98 % / sensitivity > 95 %). It permits diagnosis of active Hp gastric colonization and is useful for monitoring the efficacy of treatment.
Further information
- Resting patient, fasting for a minimum of 6 hours (no drink, no food, no smoke)
- No antibiotic treatment for 4 weeks minimum before testing
- No Proton-pump inhibitor treatment for 2 weeks minimum before testing
- No antacids and gastro-intestinal protectants 24 hours before the test
- Have the patient blow gently into 15 seconds (until mist appear), then quickly replace properly the cap on the tube
Perform the T30, 30 minutes after the T0 with a tolerance of 5 minutes more or less.
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Documents to download
Methodology
Isotopic method
Turnaround time
4 days
Biomnis Lyon