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HomeServicesTest guideAnti HMGCR antibodies - serum
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Anti HMGCR antibodies - serum

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Eurofins Biomnis code

HMGCR

Synonyms

  • 3-hydroxy-3-methyl-glutaryl-CoA reductase antibodies
  • Anti-HMG-CoA reductase Antibody

Clinic significance

Statins or inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are some of the most commonly prescribed treatments in France. Moreover, they are well known to be the cause of exercise intolerance of variable severity. Recently, they have been implicated in the occurrence of acquired inflammatory myopathies related to the existence of anti-HMGCR antibodies. The assay of anti-HMGCR antibodies (also present in 50% of thse not receiving statins) allows the diagnosis of necrotising autoimmune myopathy and commencing an effective immunosuppressant treatment.

Prenalytics

  • 1 mL
  • Serum
  • Refrigerated

Further information


    Methodology

    Chemiluminescence

    Turnaround time

    7 days


    Pathologist(s) in charge
    Biomnis Paris
    Specialty
    Immunology
    Contact(s)
    Dr Laurence GUIS
    Dr Nihad MEKNACHE
    Phone(s)
    +331 49 59 15 01
    +331 49 59 63 40

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