Anti HMGCR antibodies - serum
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HMGCR
Synonyms
- 3-hydroxy-3-methyl-glutaryl-CoA reductase antibodies
- Anti-HMG-CoA reductase Antibody
Clinic significance
Statins or inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are some of the most commonly prescribed treatments in France. Moreover, they are well known to be the cause of exercise intolerance of variable severity. Recently, they have been implicated in the occurrence of acquired inflammatory myopathies related to the existence of anti-HMGCR antibodies. The assay of anti-HMGCR antibodies (also present in 50% of thse not receiving statins) allows the diagnosis of necrotising autoimmune myopathy and commencing an effective immunosuppressant treatment.
Prenalytics
- 1 mL
- Serum
- Refrigerated
Further information
Methodology
Chemiluminescence
Turnaround time
7 days
Pathologist(s) in charge
Biomnis Paris
Specialty
Immunology
Contact(s)
Dr Laurence GUIS
Dr Nihad MEKNACHE
Dr Nihad MEKNACHE
Phone(s)
+331 49 59 15 01
+331 49 59 63 40
+331 49 59 63 40