Eurofins Biomnis code

IMFIB

Synonyms

• Fibrinogen - antigen
• Fibrinogen - quantitation
• Immunological fibrinogen

Specialty

Haematology

Clinical significance

Fibrinogen is a glycoprotein synthesized in the liver and by megakaryocytes. Increased levels are associated with inflammation, diabetes and obesity. Levels can fall if it is being heavily consumed, as in conditions like diffuse intravascular coagulation. Congenital afibrinogenemia is very unusual but there are patients with hypofibrinogenemia who are prone to hemorrhage (the severity of the bleeding symptoms is directly related to the plasma concentration of fibrinogen). Defective fibrinogen (inherited) may be suspected when a normal or nearly normal absolute fibrinogen concentration is measured in a patient whose blood takes longer than normal to clot. Bleeding symptoms (usually minor) and sometimes a tendency to thrombosis may be associated with defective fibrinogen. Smokers have higher levels than non-smokers. The quantitative fibrinogen assay screens for deficits in fibrinogen levels in order to distinguish hypofibrinogenemia disorders from dysfibrinogenemia disorders

Preanalytics

• 1 mL :
• Citrated Plasma
•   FROZEN
• Freezing within 4 hours

• A tube specifically for this analysis : No

Further information

Enclose the specific clinical information form (R5-INTGB : Haemostasis)
It is advisable to send us a frozen and centrifuged citrate sample in compliance with the GFHT pre-analytical recommendations.

Documents to download

• Specific clinical information form (R5-INTGB)

Methodology

Immuno turbidimetry

Turnaround time

1 week