Eurofins Biomnis code

INH

Synonyms

• INH
• Isoniazid
• RIMIFON

Specialty

Analytical Chemistry

Clinical significance

A major anti-tuberculosis drug. Induces liver toxicity when co-administered with rifampicin. This test helps with establishing the correct dosage and gives the acetylation phenotype. Half-life of the order of 1 hour 30 minutes at the highest normal acetylation rate and of the order of 3 hours at lower rates.

Preanalytics

• 2 mL :
• Serum (do not use tubes with separator gel)
•   FROZEN
• 1 hour

• A tube specifically for this analysis : Yes

Further information

Enclose the specific information form R8 INTGB anti-fungal agents and anti-tuberculosis drugs
Freeze the sample within 1 hour after sampling
peros: strict T+3h (possibility of associating a residual measurement: T0 + T3h)
in IV: Tmax: 1/2h after injection

Methodology

Tandem mass spectrometry (MS/MS)

Turnaround time

15 days

Caption