Eurofins Biomnis code

KIRT

Synonyms

• Killer-Cell Immunoglobulin-like Receptors
• KIR

Specialty

Genetics

Clinical significance

KIR receptors are expressed on the surface of NK cells as inhibitory and activating combinations of inhibitory and activating receptors. These combinations combinations into two haplotypes: A and B. The ligands for receptors are HLA class 1 molecules, of which HLA-C is the most important. Certain KIR-HLA combinations have an impact in the context of autoimmunity, infection, fertility, etc.

Preanalytics

• 2 x 5 mL (sang total EDTA) :
• Total EDTA blood
•   Ambient temperature

• A tube specifically for this analysis : Yes

Further information

Sample must be refrigerated if transport is > 48 hours
Complete and attach the information form available on www.eurofins-biomnis.com together with the patient request form
Copy of the CNI and signed certificate and consent are essential.
If there is a request for the spouse, please give his/her name in the patient's file (Cf. infertility molecular genetics request form).

Documents to download

• Request form

Methodology

PCR SSO

Turnaround time

4 weeks

Caption