Malondialdehyde - plasma Refered Test
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MDA
Synonyms
- MDA
- Malon dialdehyde
Clinic significance
Peroxidation marker similar to glutathione peroxidase. Malonic dialdehyde or malone-dialdehyde (MDA) is a substance appearing during the peroxidation of atherogenic lipoproteins (LDL). LDL play a vital role in early atherosclerosis development.
In-vivo oxidation of LDL converts monocytes/macrophages into spumous cells, the starting point of the atheromatous lesion. LDL peroxidation involves free radicals derived from oxygen. Of the aldehydres formed, malonic dialdehyde is the most abundant.
Increased malonic dialdehyde levels have been demonstrated in hyperlipidaemic subjects and also in inflammatory syndromes.
Prenalytics
- 1 mL
- Lithium heparin plasma
- FROZEN
Further information
- Sample to be frozen within 1 hour. Home sampling is not advisable.
- Refrigerated centrifugation
Methodology
Fluorometry
Turnaround time
3 weeks
Pathologist(s) in charge
Specialty
Contact(s)
Dr Gilles PANTEIX
Phone(s)
+334 72 80 10 41
Caption
Refered TestThe pre-analytical conditions and prices are defined on the basis of the requirements of the performing laboratory.
