Eurofins Biomnis code

NMOAC

Synonyms

• Anti Aquaporin 4 antibodies
• Anti-AQP4 antibodies
• Anti-NMO antibodies
• Neuromyelitis optica - anti-antibodies
• NMO - anti-antibodies

Specialty

Immunology

Clinical significance

Neuromyelitis optica is a demyelinating inflammation that selectively affects the optic nerve. This is a severe variant of multiple sclerosis. NMO-IgG antibodies have a sensitivity of 73% in NMO and 58% in ocular and spinal forms of multiple sclerosis. Specificity is greater than 95%. Their antigen target is aquaporin 4

Preanalytics

• 500 µL :
• serum (do not use 10 mL tube)
•   Reftrigerated

• A tube specifically for this analysis : No

Methodology

Immunofluorescence

Turnaround time

1 week