Mumps - IgG/IgM serology - serum
Back to the listEurofins Biomnis code
ORE
Synonyms
- Mumps paramyxovirus - IgG/IgM serology
- Mumps virus - IgG/IgM serology
Specialty
Infectious
Clinical significance
A highly contagious viral disease spread in airborne droplet nuclei. It has a long incubation time (20 days) and mainly affects children, causing painful swelling of one or both parotid glands. It can also involve other organs, including the sexual glands (orchitis and ovaritis after puberty), the pancreas (pancreatitis) and the central nervous system (lymphocytic meningitis and meningoencephalitis). Unproductive and asymptomatic infections can occur. Diagnosis depends on detecting (as early in infection as possible) viral antigens in nasopharyngeal swab material. The virus can be cultured from the same type of specimen or from saliva or CSF, as long as it is transported quickly and kept refrigerated. Seroconversion and the appearance of specific IgM antibodies occurs about 15 days after infection. A positive titer of IgG antibodies is indicative of protective immunity, be it following a natural infection or immunization.
Further information
Storage temperature (2-8°C) < 7 days during transport of specimen.
Methodology
Chemiluminescence
Turnaround time
2 days