Eurofins Biomnis code

OREBM

Specialty

Infectious

Clinical significance

It is an RNA virus belonging to the Paramyxoviridae family. Mumps is a viral childhood disease mainly affecting the salivary glands (often bilateral parotitis). The virus is transmitted only between human beings, by inhalation of contaminated droplets of saliva or by direct contact with saliva. The incubation period is around twenty days. The virus replicates in the oropharyngeal sphere. The infection is generally benign in children, but the two main complications may be neurological (lymphocytic meningitis) or genital (in adults, ovaritis and, in men, orchitis, which can lead to sterility). Diagnosis of parotitis is based primarily on clinical examination. If there is any doubt about the diagnosis, a serology test can be carried out. IgM antibodies are detectable from the 4th day after the onset of the first signs, but are frequently absent in vaccinated individuals. Re-infection with a different serotype of urinary tract virus (or after vaccination) may occur. The diagnosis of choice is based on techniques for detecting the virus by RT-PCR in saliva, more rarely in tracheobronchial secretions (intubated patients) or in CSF.

Preanalytics

• Saliva, nasopharynx, CSF
•   Reftrigerated

• A tube specifically for this analysis : No

Further information

[To be translated]
The use of the S14UK transport bag is Mandatory.
Swab samples require the use of a transport medium (viral) supplied in kit K1.
Samples (other than swabs) must be sent as they are, in sterile bottles, without transport medium.

Specific equipment available

• S14: Special mycobacteria transport bags are to be used

Methodology

RT - PCR in real time

Turnaround time

5 days