Eurofins Biomnis code

OSTEO

Synonyms

• BGP
• Bone GLA protein
• Bone Gla Protein

Specialty

Biochemistry

Clinical significance

A vitamin K-dependent calcium-binding bone protein. Accounts for 1 to 2% of all the protein mass in bone tissue. It is synthesized in osteoclasts and the most important factor regulating its production is 1,25 dihydroxy -(OH)2 vitamin D. Serum levels are a good indicator of bone turnover and in osteoporosis, this test can be used to estimate the rate of loss of bone tissue.

Preanalytics

• 1 mL :
• serum
•   FROZEN
• Freezing within 4 hours

• A tube specifically for this analysis : No

Further information

Gel tubes must be decanted before referral in order to avoid haemolysis at the defrosting stage.
ATTENTION: interference possible in patients treated with biotin (vitamin B7, B8 or H) or taking any food supplement containing biotin. Essential to STOP treatment 8 days before taking the sample.

Methodology

Electrochemiluminescence

Turnaround time

1 day